Single Source: Molecular Atlas of Lung Development Program (LungMAP) Phase 3 - Data Coordinating Center (U24- Clinical Trial Not Allowed) | RFA HL 24 007

Opportunity Information: Apply for RFA HL 24 007

This funding opportunity, RFA HL 24 007, is a National Institutes of Health (NIH) cooperative agreement that supports the LungMAP Phase 3 Data Coordinating Center (DCC) under the U24 mechanism, with clinical trials not allowed. The broader LungMAP program is focused on building a comprehensive molecular and cellular atlas of the human lung that can function as a reference resource for the research community. The central scientific aim is to improve understanding of normal lung biology and the mechanisms that drive lung diseases by identifying key cell types, molecular pathways, and potential therapeutic targets. A major emphasis is that LungMAP is meant to be an open access, community-facing platform rather than a closed project, so the outputs are expected to be broadly usable by investigators studying lung development and disease.

In practical terms, the LungMAP atlas is described as a multi-scale, high-content, high-resolution resource that integrates different kinds of data to define lung cells and their states. This includes mapping gene expression patterns, physiological or functional states, and 3-dimensional spatial locations of cells within lung tissue, along with how cells change over time across developmental trajectories and in pathological contexts. The Data Coordinating Center role implied by this description is to serve as the hub that organizes, harmonizes, curates, and disseminates these complex datasets so they can be integrated into a coherent atlas. Because the opportunity is a cooperative agreement, it also signals substantial NIH scientific and programmatic involvement in the project, meaning the awardee typically collaborates closely with NIH staff and other LungMAP-funded components to meet shared program goals, coordinate standards, and deliver interoperable data products.

The opportunity falls under the Health funding activity category (CFDA 93.838) and is administered by NIH. The listed award ceiling is $1,260,000, and the original closing date provided is 2023-10-27. While the specific number of expected awards is not clearly stated in the provided text, the title includes "Single Source," which commonly indicates NIH intends to support one primary coordinating center for this function, aligning with the concept of a centralized DCC.

Eligibility is broad and includes many types of U.S.-based organizations and governmental entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; other Native American tribal organizations; public housing authorities/Indian housing authorities; nonprofits with and without 501(c)(3) status (as long as they are not institutions of higher education in those categories); for-profit organizations (other than small businesses); and small businesses. The announcement also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

Foreign eligibility is limited in a specific way. Non-domestic (non-U.S.) entities and non-U.S. foreign institutions are not eligible to apply directly as applicant organizations. However, non-domestic components of U.S. organizations are eligible to apply, and foreign components, as defined in the NIH Grants Policy Statement, are allowed. In other words, the applicant must be a domestic eligible organization, but parts of the work may include foreign components if they meet NIH policy requirements.

Overall, the opportunity is designed to fund the infrastructure and leadership needed to coordinate LungMAP Phase 3 data into a unified, openly accessible atlas of the human lung. The expected value is not only in generating data, but in making the data reliable, standardized, integrated across scales (molecular, cellular, spatial, developmental), and easy for the broader scientific community to find, use, and build upon in studies of lung development and lung disease mechanisms.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Single Source: Molecular Atlas of Lung Development Program (LungMAP) Phase 3 - Data Coordinating Center (U24- Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.838.
• This funding opportunity was created on 2023-07-14.
• Applicants must submit their applications by 2023-10-27. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $1,260,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA HL 24 007

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