Opportunity Information: Apply for RFA DK 20 014
The Reconfiguration of the GenitoUrinary Development Molecular Anatomy Project (GUDMAP) and (Re)Building a Kidney (RBK) Data Hub funding opportunity (RFA DK 20 014) is a National Institutes of Health cooperative agreement (U24; clinical trial not allowed) intended to support a single, consolidated Data Hub that serves both the GUDMAP and RBK research communities. The core idea is to create and operate a robust, searchable, web-based repository where consortium-generated data and related resources can be submitted, curated, standardized, and made broadly useful to researchers studying genitourinary development and kidney reconstruction. Beyond simply hosting files, the hub is expected to function as the central connective tissue for these consortia by making the data easy to find, access, integrate, and reuse, while also supporting coordination and collaboration across participating groups.
A major emphasis of the announcement is implementation of FAIR data principles: Findable, Accessible, Interoperable, and Reusable. In practice, that means the Data Hub is expected to support strong metadata standards, consistent identifiers, clear data access mechanisms, and technical approaches that allow datasets to be combined or compared across studies and platforms. The hub is also expected to bring the right domain-specific expertise to the table, including bioinformatics capabilities, modern website and software development, and high-quality biocuration. The announcement specifically highlights ontology development and the need for subject-matter expertise in relevant organ anatomy and physiology, reflecting the importance of consistent anatomical and developmental terminology for organizing and interpreting complex biological datasets.
The Data Hub is designed to carry both scientific and administrative responsibilities. Scientifically, it must support data intake, quality control, harmonization, and user-friendly discovery tools that help researchers search and analyze the information. Administratively, it is expected to help manage consortium-facing activities such as planning and running workshops and providing coordination support that keeps the community aligned on standards, priorities, and shared resources. This dual role signals that NIH is looking for an awardee that can run a dependable production-grade informatics platform while also acting as an effective organizer and service center for a geographically distributed scientific network.
A distinctive component of this opportunity is oversight of an Opportunity Pool Program. This program is intended to actively promote collaboration by helping spark new partnerships and by funding or enabling targeted efforts that expand or enhance the database and its capabilities. In other words, the hub is not meant to be static; it is expected to continually evolve based on user needs, emerging methods, and new types of data, while also serving as a catalyst for cross-team collaboration within and around GUDMAP and RBK.
The award is offered by the U.S. Department of Health and Human Services through NIH, with an activity focus that falls under health-related research and infrastructure (CFDA 93.847). The funding mechanism is a cooperative agreement, which typically implies substantial NIH program involvement, ongoing coordination, and shared stewardship of goals and deliverables compared with a standard grant. The opportunity anticipated one award, with an annual award ceiling listed at $750,000. The original posting indicates a creation date of November 23, 2020, and an original closing date of February 18, 2021.
Eligibility is broad and includes many types of domestic organizations that can credibly run a national-scale data resource and provide sustained technical and administrative support. Eligible applicants include state, county, and local governments; public and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; federally recognized tribal governments and other tribal organizations; public housing authorities; for-profit organizations (including small businesses and other than small businesses); and other entities as described in the full eligibility text. Overall, the opportunity targets teams with demonstrated strength in biomedical data infrastructure, curation and standards, and community-facing coordination, with the explicit goal of delivering a unified GUDMAP/RBK Data Hub that improves data usability, accelerates discovery, and strengthens collaboration across the kidney and genitourinary development research ecosystem.Apply for RFA DK 20 014
- The Department of Health and Human Services, National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Reconfiguration of GenitoUrinary Development Molecular Anatomy Project (GUDMAP) /(Re)Building A Kidney (RBK) Data Hub (U24 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
- This funding opportunity was created on Nov 23, 2020.
- Applicants must submit their applications by Feb 18, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $750,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
What is the RFA DK 20 014 funding opportunity?
RFA DK 20 014 is a National Institutes of Health (NIH) cooperative agreement funding opportunity (U24; clinical trial not allowed) focused on the Reconfiguration of the GenitoUrinary Development Molecular Anatomy Project (GUDMAP) and (Re)Building a Kidney (RBK) Data Hub.
What is the main purpose of this award?
The purpose is to support a single, consolidated Data Hub that serves both the GUDMAP and RBK research communities by creating and operating a robust, searchable, web-based repository for consortium-generated data and related resources.
How many awards are anticipated under this opportunity?
The opportunity anticipates a single award to support one consolidated Data Hub serving both consortia.
What is the funding mechanism and what does it imply?
The funding mechanism is a cooperative agreement (U24). This typically implies substantial NIH program involvement, ongoing coordination, and shared stewardship of goals and deliverables compared with a standard research grant.
Are clinical trials allowed under this award?
No. The opportunity is explicitly described as U24 with clinical trial not allowed.
What is the annual award ceiling?
The annual award ceiling listed for this opportunity is $750,000.
Which federal agency is offering this opportunity?
The award is offered by the U.S. Department of Health and Human Services through the National Institutes of Health (NIH).
What is the CFDA number and program area?
The activity focus is described as health-related research and infrastructure under CFDA 93.847.
What communities is the Data Hub intended to serve?
The Data Hub is intended to serve both the GUDMAP and RBK research communities, acting as a shared resource and central platform for data and related resources generated by these consortia.
What kinds of data or resources are expected to be handled by the Data Hub?
Based on the announcement, the hub is expected to accept consortium-generated data and related resources, support submission and curation, standardize and harmonize content, and make the resulting datasets broadly useful to researchers studying genitourinary development and kidney reconstruction.
Is the Data Hub just a file hosting site?
No. The hub is expected to go beyond file hosting by making data easy to find, access, integrate, and reuse, and by supporting coordination and collaboration across participating groups.
What does it mean that the hub should be "searchable" and "web-based"?
It means the Data Hub should be implemented as an online platform with user-facing discovery tools that enable researchers to search for, locate, and work with curated datasets and related resources through a web interface.
What are FAIR data principles and how do they apply here?
FAIR stands for Findable, Accessible, Interoperable, and Reusable. The opportunity emphasizes implementing these principles through strong metadata standards, consistent identifiers, clear access mechanisms, and technical approaches that allow datasets to be combined or compared across studies and platforms.
What are the key technical expectations for the Data Hub?
The hub is expected to provide production-grade informatics capabilities including data submission workflows, biocuration, quality control, harmonization/standardization, robust metadata and identifiers, and user-friendly discovery tools that support searching and analysis.
What role does metadata play in this opportunity?
Metadata is central to making data findable and reusable. The opportunity highlights strong metadata standards as part of FAIR implementation, enabling consistent descriptions of datasets and better discovery, comparison, and integration across studies.
Why are ontologies specifically highlighted?
Ontology development is highlighted because consistent anatomical and developmental terminology is critical for organizing, connecting, and interpreting complex biological datasets in genitourinary development and kidney reconstruction research.
What subject-matter expertise is expected for the Data Hub team?
The opportunity calls for domain-specific expertise relevant to organ anatomy and physiology (in the genitourinary/kidney context), along with bioinformatics capabilities, modern website and software development, and high-quality biocuration expertise.
What scientific responsibilities does the Data Hub have?
Scientifically, the hub must support data intake, quality control, harmonization/standardization, and discovery tools that help researchers search and analyze the data.
What administrative responsibilities does the Data Hub have?
Administratively, the hub is expected to help manage consortium-facing activities such as planning and running workshops and providing coordination support to keep the community aligned on standards, priorities, and shared resources.
What is meant by the Data Hub being the "central connective tissue" for the consortia?
It means the hub is expected to function as a central organizing and enabling platform that connects participating groups through shared data standards, coordinated processes, and common tools that improve access, integration, and reuse of consortium data.
What is the Opportunity Pool Program and who oversees it?
The Opportunity Pool Program is a distinctive component of the award that the Data Hub is expected to oversee. It is intended to promote collaboration by helping spark new partnerships and by funding or enabling targeted efforts that expand or enhance the database and its capabilities.
Is the Data Hub expected to remain static once launched?
No. The opportunity describes the hub as something that should continually evolve based on user needs, emerging methods, and new types of data, while also serving as a catalyst for collaboration within and around GUDMAP and RBK.
What is the expected relationship between the awardee and NIH?
Because this is a cooperative agreement, the relationship is expected to involve substantial NIH program involvement and ongoing coordination around goals and deliverables.
Who is eligible to apply for this opportunity?
Eligibility is broad and includes many types of domestic organizations, including: state, county, and local governments; public and private institutions of higher education; nonprofit organizations with or without 501(c)(3) status; federally recognized tribal governments and other tribal organizations; public housing authorities; for-profit organizations (including small businesses and other than small businesses); and other entities as described in the full eligibility text.
Does the opportunity appear limited to academic institutions only?
No. The eligibility list includes academic institutions, nonprofits, governments, tribal organizations, public housing authorities, and for-profit entities including small businesses.
What kinds of organizations are best positioned to compete for this award (based on the description)?
The opportunity targets teams that can credibly run a national-scale data resource and provide sustained technical and administrative support, with demonstrated strength in biomedical data infrastructure, curation and standards, and community-facing coordination.
What are the key outcomes NIH appears to want from this Data Hub?
The described goal is a unified GUDMAP/RBK Data Hub that improves data usability, accelerates discovery, and strengthens collaboration across the kidney and genitourinary development research ecosystem.
What are the original posting and closing dates listed for this opportunity?
The original creation date is listed as November 23, 2020, and the original closing date is listed as February 18, 2021.
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