Opportunity Information: Apply for PAR 25 449
The National Center for Complementary and Integrative Health (NCCIH) is offering funding through a phased grant opportunity to study how mind and body interventions—such as mindfulness, yoga, acupuncture, and massage—affect emotional well-being and its connection to whole person health. The grant supports clinical trials focused on understanding the mechanisms behind how these practices improve emotional well-being (the primary outcome), and their relationship with whole person health, assessed using the Whole Person Health Index (a secondary outcome).
This funding opportunity uses a two-phase R61/R33 mechanism. The R61 phase supports establishing feasibility and initial benchmarks, and is required before moving to the R33 phase, which funds the full-scale clinical trial. Progression to the second phase depends on successful completion of specific goals during the first.
Applicants must provide strong preliminary data comparable in quality and depth to an NIH R01 proposal. A wide range of U.S.-based organizations are eligible to apply, including minority-serving institutions, tribal organizations, faith-based groups, and regional bodies. Foreign organizations or non-U.S. components are not eligible.Apply for PAR 25 449
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Mind and Body Interventions to Restore Whole Person Health via Emotional Well-Being Mechanisms (R61/R33 Clinical Trial Required)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213.
- This funding opportunity was created on 2025-09-26.
- Applicants must submit their applications by 2028-06-07.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Previous opportunity: CY25 Annual SCMF/CHSP Renewal
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