Opportunity Information: Apply for PAR 24 268
The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (PAR-24-268) is a National Institutes of Health (NIH) funding opportunity designed to help expand participation in biomedical research by strengthening institutions that have historically had limited research resources. The focus is not only on supporting research activities themselves, but also on improving the overall research environment and building the internal administrative capacity needed to successfully manage and grow externally sponsored research. In practical terms, the program is meant to help eligible organizations become more competitive and sustainable in the biomedical research ecosystem by investing in both the research side and the grants management infrastructure that makes research possible.
This opportunity uses a cooperative agreement mechanism (UC2), which generally means NIH expects to have substantial involvement during the project period compared with a standard grant. The notice specifies "Clinical Trial Not Allowed," signaling that applicants must propose activities that do not include clinical trials as defined by NIH. The funded work is therefore expected to center on non-clinical-trial research and capacity-building efforts, such as strengthening institutional research systems, improving infrastructure and processes that support investigators, and enhancing sponsored programs administration functions (for example, pre-award and post-award support, compliance capabilities, and institutional policies and workflows that enable effective grant management).
The program is explicitly targeted to domestic, resource-limited organizations, particularly those with few biomedical doctoral students and limited research capacity. While the detailed eligibility rules are in the full Notice of Funding Opportunity (NOFO), the summary highlights several categories of institutions that are specifically included among eligible applicants, reflecting the program's emphasis on broadening participation and supporting under-resourced educational and research environments. These include Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). The broader eligible applicant types listed also include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both with and without 501(c)(3) status), as well as other entities as allowed under the NOFO.
Strict geographic and organizational restrictions apply. Non-U.S. (foreign) organizations are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible. In addition, foreign components as defined by the NIH Grants Policy Statement are not allowed, which reinforces that the proposed programmatic activities must be carried out without foreign components and within allowable domestic settings.
Key administrative details indicate this is a discretionary funding opportunity from NIH, categorized under education and health-related activities, and associated with multiple CFDA/Assistance Listing numbers (93.121, 93.213, 93.242, 93.273, 93.279, 93.310, 93.846, 93.853, 93.859, 93.866, 93.867), reflecting NIH institute and center participation across several biomedical domains. The opportunity was created on 2024-10-30, and the original closing date is 2027-01-27, giving prospective applicants a relatively long planning horizon (though applicants should confirm application due dates, cycles, and any submission windows or renewals in the NOFO). The listed award ceiling is $500,000, indicating the maximum amount expected per award under this announcement, although final budgets and project scopes must align with NIH rules and the specific requirements laid out in the NOFO. The number of expected awards is not specified in the provided data.
Overall, BRE-SPAD is aimed at helping eligible U.S.-based institutions strengthen their ability to conduct and sustain biomedical research by investing in both the research environment and the sponsored programs administration backbone that supports proposal development, compliance, award management, and long-term growth in external research funding, without supporting clinical trials under this UC2 mechanism.Apply for PAR 24 268
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program (UC2- Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121, 93.213, 93.242, 93.273, 93.279, 93.310, 93.846, 93.853, 93.859, 93.866, 93.867.
- This funding opportunity was created on 2024-10-30.
- Applicants must submit their applications by 2027-01-27.
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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BRE-SPAD (PAR-24-268) FAQs
What is the BRE-SPAD Program (PAR-24-268)?
The Biomedical Research Environment and Sponsored Programs Administration Development (BRE-SPAD) Program is a National Institutes of Health (NIH) funding opportunity designed to expand participation in biomedical research by strengthening institutions that have historically had limited research resources. It supports both research-related capacity building and improvements to the internal administrative systems needed to manage and grow externally sponsored research.
What is the main goal of this NIH opportunity?
The goal is to help eligible, resource-limited domestic institutions become more competitive and sustainable in the biomedical research ecosystem by investing in the research environment and in sponsored programs administration capacity (the infrastructure and processes that enable successful grant seeking and grant management).
Does BRE-SPAD fund research activities, administrative capacity building, or both?
Both. The program is intended to strengthen the overall research environment and also build the internal administrative capacity that supports sponsored research, such as proposal development support, compliance, and post-award management functions.
What funding mechanism is used for this opportunity?
This opportunity uses a cooperative agreement mechanism (UC2). This generally means NIH expects to have substantial involvement during the project period compared to a standard grant.
What does it mean that this is a cooperative agreement (UC2)?
Based on the description provided, NIH anticipates substantial involvement during the project period. In practical terms, applicants should expect more active participation by NIH than occurs under many standard grant mechanisms.
Are clinical trials allowed under BRE-SPAD?
No. The notice specifies "Clinical Trial Not Allowed," meaning applicants must propose activities that do not include clinical trials as defined by NIH.
If clinical trials are not allowed, what kinds of activities are expected?
The funded work is expected to center on non-clinical-trial research and capacity-building efforts. Examples mentioned include strengthening institutional research systems, improving infrastructure and processes that support investigators, and enhancing sponsored programs administration functions such as pre-award and post-award support, compliance capabilities, and institutional policies and workflows for effective grant management.
Who is this program intended to help?
The program is explicitly targeted to domestic, resource-limited organizations, particularly those with few biomedical doctoral students and limited research capacity.
What types of institutions are specifically highlighted as eligible?
The summary highlights several categories of institutions specifically included among eligible applicants: Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
What other applicant organization types are listed as eligible?
The broader eligible applicant types listed include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both with and without 501(c)(3) status), as well as other entities as allowed under the NOFO.
Are foreign (non-U.S.) organizations eligible to apply?
No. Non-U.S. (foreign) organizations are not eligible to apply.
Can a U.S. organization apply if the project includes a non-U.S. component?
No. Non-U.S. components of U.S. organizations are not eligible. In addition, foreign components (as defined by the NIH Grants Policy Statement) are not allowed, reinforcing that proposed activities must be carried out without foreign components and within allowable domestic settings.
What does the restriction on "foreign components" imply for project planning?
It implies the proposed programmatic activities must be carried out domestically and cannot include foreign components as defined by NIH policy.
Which federal agency is offering this funding opportunity?
The funding opportunity is offered by the National Institutes of Health (NIH).
Is this a discretionary grant opportunity?
Yes. The information provided describes it as a discretionary funding opportunity from NIH.
What general topic areas does this opportunity fall under?
It is categorized under education and health-related activities, with a focus on strengthening biomedical research participation and sponsored research administration capacity.
What is the maximum award amount (award ceiling) listed for this opportunity?
The listed award ceiling is $500,000, which indicates the maximum amount expected per award under this announcement. Final budgets and project scopes must align with NIH rules and the requirements in the NOFO.
Is the number of awards known?
No. The number of expected awards is not specified in the provided information.
When was this opportunity created?
The opportunity was created on 2024-10-30.
What is the original closing date for this opportunity?
The original closing date listed is 2027-01-27.
Does the long closing date mean I can apply at any time until 2027-01-27?
Not necessarily. The provided summary notes a relatively long planning horizon, but applicants should confirm application due dates, cycles, and any submission windows (and any renewals) in the full Notice of Funding Opportunity (NOFO).
Where are the detailed eligibility rules and application requirements?
The detailed eligibility rules and other requirements are in the full Notice of Funding Opportunity (NOFO), referenced in the summary.
What kinds of internal administrative functions does BRE-SPAD aim to strengthen?
Examples listed include sponsored programs administration functions such as pre-award and post-award support, compliance capabilities, and institutional policies and workflows that enable effective grant management.
What does "sponsored programs administration" refer to in this context?
In this context, it refers to the internal grants management and research administration backbone that supports proposal development, compliance, award management, and long-term growth in external research funding.
What is the broader purpose of strengthening the research environment and administrative capacity?
The broader purpose is to help eligible institutions conduct and sustain biomedical research more effectively and to become more competitive for external (sponsored) funding over the long term.
What Assistance Listing (CFDA) numbers are associated with this opportunity?
The opportunity is associated with multiple CFDA/Assistance Listing numbers: 93.121, 93.213, 93.242, 93.273, 93.279, 93.310, 93.846, 93.853, 93.859, 93.866, 93.867.
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