Opportunity Information: Apply for PA 22 050
The AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Clinical Scientist Career Development Award (K08), Funding Opportunity Number PA-22-050, is a discretionary grant program run by the Agency for Healthcare Research and Quality (AHRQ). Its central goal is to build the next generation of independent clinician-scientists by funding an intensive, mentored career development experience focused on comparative effectiveness research (CER) methods as they are used in patient-centered outcomes research (PCOR). In practical terms, the opportunity is designed for qualified individuals who want structured mentorship, protected time, and methodologic training so they can develop the skills to design and carry out rigorous studies that compare healthcare interventions, strategies, or delivery approaches and evaluate outcomes that matter to patients.
The emphasis on CER methods applied to PCOR signals what AHRQ is trying to produce through this award: investigators who can use strong, modern research approaches to answer real-world clinical and health system questions with a patient-centered lens. Rather than focusing only on efficacy under ideal conditions, CER commonly addresses what works best for which patients, in which settings, and under which real-world constraints, while PCOR places additional weight on outcomes meaningful to patients and caregivers (such as function, symptoms, quality of life, and burden of care), along with patient priorities and preferences. The K08 structure also implies a mentored pathway where the award supports a deliberate transition from a mentored stage to independent research leadership in health services research and outcomes research.
Eligibility for applicants is broad across U.S.-based organizations that can support the proposed career development and research environment. Eligible applicant organizations include state governments; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized); and Native American tribal organizations (other than federally recognized tribal governments). The opportunity also explicitly highlights additional eligible applicant types that often align with efforts to broaden participation and strengthen research capacity in diverse settings, including Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); faith-based or community-based organizations; Hispanic-serving institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs). At the same time, the announcement is clear that non-domestic (non-U.S.) entities are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible, keeping the program squarely focused on domestic U.S. institutions and infrastructure.
From an administrative standpoint, this is a grant mechanism in the health funding activity category, associated with CFDA number 93.226. The posting lists an original closing date of March 12, 2025, and a creation date of December 8, 2021. The provided source data does not specify an award ceiling or the expected number of awards, so prospective applicants would typically confirm current budget limits, allowable costs, and expected funding levels in the full funding announcement and related AHRQ guidance. Overall, the opportunity can be understood as a mentored clinician-scientist career development pathway aimed at strengthening the field of patient-centered comparative effectiveness research by investing in people, mentorship, and methodologic development within eligible U.S. institutions.Apply for PA 22 050
- The Agency for Health Care Research and Quality in the health sector is offering a public funding opportunity titled "AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Clinical Scientist Career Development Award (K08)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.226.
- This funding opportunity was created on 2021-12-08.
- Applicants must submit their applications by 2025-03-12. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Private institutions of higher education, Others.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
FAQs: AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Clinical Scientist Career Development Award (K08) - PA-22-050
What is this funding opportunity?
This opportunity is the AHRQ Patient-Centered Outcomes Research (PCOR) Mentored Clinical Scientist Career Development Award (K08), Funding Opportunity Number PA-22-050. It is a discretionary grant program administered by the Agency for Healthcare Research and Quality (AHRQ).
What is the main goal of this K08 award?
The central goal is to build the next generation of independent clinician-scientists by funding an intensive, mentored career development experience. The focus is on learning and applying comparative effectiveness research (CER) methods within patient-centered outcomes research (PCOR), with the longer-term intent of helping awardees transition from mentored research to independent research leadership.
Who is this award designed to support?
It is designed for qualified individuals seeking structured mentorship, protected time, and methodologic training to develop the skills needed to design and conduct rigorous studies that compare healthcare interventions, strategies, or delivery approaches and evaluate outcomes that matter to patients.
What research emphasis does AHRQ highlight for this K08?
The emphasis is on comparative effectiveness research (CER) methods as they are used in patient-centered outcomes research (PCOR). The program aims to develop investigators who can answer real-world clinical and health system questions using strong, modern research approaches that keep patient priorities and meaningful outcomes at the center of the work.
What does "comparative effectiveness research (CER)" mean in the context of this program?
In this program context, CER commonly focuses on what works best for which patients, in which settings, and under real-world constraints. It is presented as distinct from research that only tests efficacy under ideal conditions, emphasizing practical comparisons among interventions, strategies, or care delivery approaches.
What does "patient-centered outcomes research (PCOR)" mean in the context of this program?
PCOR, as described here, places additional weight on outcomes meaningful to patients and caregivers, such as function, symptoms, quality of life, and burden of care. It also emphasizes patient priorities and preferences when framing and evaluating research questions and outcomes.
How does the mentored K08 structure fit into career development?
The K08 structure indicates a mentored pathway intended to support a deliberate transition from a mentored stage to independent research leadership. The award supports a career development and research environment built around mentorship, protected time, and methodologic growth in health services research and outcomes research.
Which organizations are eligible to apply?
Eligible applicant organizations include U.S.-based entities such as state governments; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized); and Native American tribal organizations (other than federally recognized tribal governments).
Which additional applicant organization types are explicitly highlighted as eligible?
The opportunity explicitly highlights additional eligible types including Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); faith-based or community-based organizations; Hispanic-serving institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs).
Are non-U.S. (non-domestic) organizations eligible to apply?
No. The announcement states that non-domestic (non-U.S.) entities are not eligible to apply.
Can a U.S. organization include a non-domestic component in the proposed work?
No. Non-domestic components of U.S. organizations are also not eligible, keeping the program focused on domestic U.S. institutions and infrastructure.
What funding activity category is associated with this opportunity?
The opportunity is listed under a health funding activity category.
What is the CFDA number associated with this program?
The CFDA number associated with this opportunity is 93.226.
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA-22-050.
What is the original closing date listed for this opportunity?
The posting lists an original closing date of March 12, 2025.
What is the creation date listed for the opportunity?
The creation date listed is December 8, 2021.
Does the provided information specify an award ceiling or the expected number of awards?
No. The provided source data does not specify an award ceiling or the expected number of awards.
What should applicants do if they need details on budget limits or allowable costs?
Because the provided information does not include budget limits, allowable costs, or expected funding levels, prospective applicants would typically confirm those details in the full funding announcement and related AHRQ guidance.
In plain terms, what is AHRQ trying to produce through this award?
AHRQ is aiming to develop clinician-scientists who can independently lead patient-centered comparative effectiveness research using rigorous methods, and who can evaluate healthcare interventions and delivery approaches based on outcomes that are meaningful to patients in real-world settings.
Browse more opportunities from the same category: Health
Next opportunity: Pilot Practice-based Research for Primary Care Suicide Prevention (R34 Clinical Trial Optional)
Previous opportunity: OPE: Higher Education Emergency Relief Fund (HEERF), Section 2003 of the American Rescue Plan (ARP) for Institutions of Higher Education (IHE) that meet the criteria as a Strengthening Institutions Program (SIP), Assistance Listing Number 84.425M
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for PA 22 050
Applicants also applied for:
Applicants who have applied for this opportunity (PA 22 050) also looked into and applied for these:
| Funding Opportunity |
|---|
| Multi-Disciplinary Collaborations to Understand Mechanisms of Systemic Immune Signaling and Inflammation in ADRD and its Progression (R01 Clinical Trial Not Allowed) Apply for PAR 22 023 Funding Number: PAR 22 023 Agency: National Institutes of Health Category: Health Funding Amount: $499,000 |
| Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Phase I: Data Analysis and Validation Centers (U24 Clinical trials not allowed) Apply for RFA HG 21 031 Funding Number: RFA HG 21 031 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Phase I: Data Analysis and Validation Centers (U01 Clinical trials not allowed) Apply for RFA HG 21 030 Funding Number: RFA HG 21 030 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Molecular Phenotypes of Null Alleles in Cells (MorPhiC) Phase 1: Data Production Research and Development Centers (UM1)(Clinical trials not allowed) Apply for RFA HG 21 029 Funding Number: RFA HG 21 029 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Reducing Racial and Ethnic Healthcare Disparities in Chronic Conditions by Dissemination and Implementation of Patient Centered Outcomes Research (PCOR) Evidence (R18) Apply for RFA HS 22 001 Funding Number: RFA HS 22 001 Agency: Agency for Health Care Research and Quality Category: Health Funding Amount: $1,500,000 |
| Resource Center for Tribal Epidemiological Centers (RC-TEC) (U24 Clinical Trial Not Allowed) Apply for RFA MD 21 003 Funding Number: RFA MD 21 003 Agency: National Institutes of Health Category: Health Funding Amount: $2,000,000 |
| Clinical and Biological Measures of TBI-related Dementia Including Chronic Traumatic Encephalopathy (R01 Clinical Trial Not Allowed) Apply for PAR 22 024 Funding Number: PAR 22 024 Agency: National Institutes of Health Category: Health Funding Amount: $1,000,000 |
| Creating an Educational Nexus for Training in Experimental Rigor (CENTER) (UC2 Clinical Trial Not Allowed) Apply for RFA NS 21 009 Funding Number: RFA NS 21 009 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Dementia Care and Caregiver Support Intervention Research (R01 Clinical Trial Required) Apply for PAR 21 307 Funding Number: PAR 21 307 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Pragmatic Trials for Dementia Care and Caregiver Support (R61/R33 Clinical Trial Required) Apply for PAR 21 308 Funding Number: PAR 21 308 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Feasibility Studies that Explore Healthy and Diseased Temporomandibular Joints (TMJ) using Single Cell Multi-Omic Analyses (UH2/UH3 Clinical Trial Not Allowed) Apply for RFA DE 22 005 Funding Number: RFA DE 22 005 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Innovative Mental Health Services Research Not Involving Clinical Trials (R01 Clinical Trials Not Allowed) Apply for PAR 21 316 Funding Number: PAR 21 316 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Limited Competition: Genome Sequencing Center for the Gabriella Miller Kids First Pediatric Research Program (U24 Clinical Trial Not Allowed) Apply for RFA RM 21 013 Funding Number: RFA RM 21 013 Agency: National Institutes of Health Category: Health Funding Amount: $7,200,000 |
| Selectively Target Technology Development to Understand How Changes or Dysfunction at the Capillary, Arterioles, and Small Lymphatic Vessels Level Can Have Long-term Impact on AD/ADRD (R01 Clinical Trial Not Allowed) Apply for PAR 22 026 Funding Number: PAR 22 026 Agency: National Institutes of Health Category: Health Funding Amount: $499,000 |
| Deciphering Immune-CNS interactions in HIV utilizing in-vitro and in-vivo model systems (R21 Clinical Trial Not Allowed) Apply for RFA MH 21 251 Funding Number: RFA MH 21 251 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Deciphering Immune-CNS interactions in people living with HIV on Anti-Retroviral therapy (R01 Clinical Trial Optional) Apply for RFA MH 21 250 Funding Number: RFA MH 21 250 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| HIV Prevention and Alcohol (R01 Clinical Trials Optional) Apply for RFA AA 21 016 Funding Number: RFA AA 21 016 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
| HIV Prevention and Alcohol (R34 Clinical Trials Optional) Apply for RFA AA 21 017 Funding Number: RFA AA 21 017 Agency: National Institutes of Health Category: Health Funding Amount: $450,000 |
| Blueprint Medtech: Small Business Translator (U44 - Clinical Trial Optional) Apply for PAR 21 282 Funding Number: PAR 21 282 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Limited Competition: Continued Development of the Gabriella Miller Kids First Pediatric Data Resource Center (U2C Clinical Trial Not Allowed) Apply for RFA RM 21 014 Funding Number: RFA RM 21 014 Agency: National Institutes of Health Category: Health Funding Amount: $4,000,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "PA 22 050", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.